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How do pain relievers work in the body? When you take a pain reliever like ibuprofen, it keeps injured or damaged cells from making and releasing prostaglandin. When the cells don't release this chemical, it means that the brain won't get the pain message as quickly or clearly. Acetaminophen works in the brain so you don't feel the pain.
What can I take for pain if I can't take NSAIDs? Acetaminophen. For pain relief, try acetaminophen (Tylenol, other brands) first. Understand that acetaminophen does not target inflammation, so if your arthritis pain comes with swelling, acetaminophen may not serve your needs completely. Taking too much can damage the liver, so take only what your doctor says is safe.
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