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Why is levodopa the mainstay of treatment for a patient with Parkinson disease? Levodopa remains the mainstay treatment for Parkinson's disease (PD). Entacapone reduces homocysteine plasma levels which could provide a mechanism to reduce cell death in PD. Currently, the combination levodopa -carbidopa-entacapone is particularly indicated for the treatment of "wearing off" fluctuations.
What kills a person with Parkinson's disease? There is no definitive diagnosis of Parkinson's disease until death. Parkinson's disease doesn't kill you. Symptoms it causes can lead to problems that do – such as problems with swallowing leading to choking and pneumonia, or falling and breaking a bone or hitting the head, and then never fully recovering.
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